War Related Illness and Injury Study Center

Medically Unexplained Symptoms

• Nadkarni S, Ecker AH, Waid-Ebbs JK, Pickett LC, Ray K, Chandler HK, McAndrew LM, Helmer DA. Assessing Change in Participation in Clinical Evaluations of Deployed Veterans with Medically Unexplained Symptoms.
  Health Soc Work. 2022 Oct 29;47(4):253-261. doi: 10.1093/hsw/hlac024.PMID: 36099160.
• McAndrew LM, Quigley KS, Lu SE, Litke D, Rath JF, Lange G, Santos SL, Anastasides N, Petrakis BA, Greenberg L, Helmer DA, Pigeon WR. Effect of Problem-solving Treatment on Self-reported Disability Among Veterans With Gulf War Illness: A Randomized Clinical Trial.
  JAMA Netw Open. 2022 Dec 1;5(12):e2245272. doi: 10.1001/jamanetworkopen.2022.45272.PMID: 36472870.
• Winograd DM, Hyde JK, Bloeser K, Santos SL, Anastasides N, Petrakis BA, Pigeon WR, Litke DR, Helmer DA, McAndrew LM. Exploring the acceptability of behavioral interventions for veterans with persistent "medically unexplained" physical symptoms.
  J Psychosom Res. 2023 Apr;167:111193. doi: 10.1016/j.jpsychores.2023.111193. Epub 2023 Feb 14.PMID: 36822031
• Ninneman JV, Gretzon NP, Stegner AJ, Lindheimer JB, Falvo MJ, Wylie GR, Dougherty RJ, Almassi NE, Van Riper SM, Boruch AE, Dean DC, Koltyn KF, Cook DB. The Intersection of Chronic Musculoskeletal Pain, Physical Activity, and Brain Gray Matter in Gulf War Veterans.
  J Neurosci 2022 Jun 13:JN-RM-2394-21. doi: 10.1523/JNEUROSCI.2394-21.2022.
• Kane, N.S., Anastasides, N., Litke, D.R., Helmer, D.A., Hunt, S.C., Quigley, K.S., Pigeon, W.R., & McAndrew, L.M.* (2021). Under diagnosis of medically unexplained conditions in US Veterans with Gulf War Illness.
  Plos One. https://doi.org/10.1371/journal.pone.0259341
• Schneider, A.H., Bair, M.J., Helmer, D.A., Hyde, J., Litke, D.A., Lu, S-E , Rogers, E.S., Sherman, S.E., Sotolongo, A., Anastasides, N., Sullivan, N., Graff, F., & McAndrew, L.M.* (2021). Protocol for a type 1 hybrid effectiveness/implementation clinical trial of collaborative specialty care for Veterans with Gulf War Illness.
  Life Sciences, https://doi.org/10.1016/j.lfs.2021.120004.
• Nadkarni, S., Ecker, A.H., Waid-Ebbs, J.K., Pickett, L., Ray, K., Chandler, H.K., McAndrew, L.M., & Helmer, D.A. (In Press). Assessing Change in Participation in Clinical Evaluations of Deployed Veterans with Medically Unexplained Symptoms.
  Health and Social Work.
• Phillips, L.A., & McAndrew, L.M.* (2021). Symptom Attribution to a Medically Unexplained Syndrome is associated with Greater Perceived Severity and Bothersomeness of Symptoms in US Military Veterans.
  Psychology & Health.
• McAndrew, L.M., Khatib, L., Sullivan, N., Winograd, D.M., Kohler, S., & Santos, S. (2021). Healthcare Providers’ Perceived Learning Needs and Barriers to Providing Care for Chronic Multisymptom Illness and Environmental Exposure Concerns.
  Life Science.
• Bloeser, K., McCarron, K., Merker, V.L., Hyde, J., Bolton, R., Anastasides, N., Petrakis, BA, Helmer, D., Santos, S., Litke, D., Pigeon, W.R., & McAndrew, L.M* (2021) “Because the country, it seems though, has turned their back on me”: Experiences of institutional betrayal among veterans living with Gulf War Illness.
  Social Science and Medicine.
• Winograd, D.M., Sullivan, N., Thien, S.R., Pigeon, W., Quigley, K.S., Litke, D.R., Helmer, D.A., Rath, J., Lu, S-E, & McAndrew, L.M.* (2021). Patients with persistent medically unexplained physical symptoms perceptions of self-management strategies.
  Life Sciences. https://doi.org/10.1016/j.lfs.2021.119219
• Winograd, D. M., Fresquez, C. L., Egli, M., Peterson, E. K., Lombardi, A., Megale, A., Cabrera Tineo, Y. A., Verile, M. G., Phillips, L. A., Breland, J. Y., Santos, S., & McAndrew, L. M.* (2021). Rapid review of virus risk communication interventions: Directions for COVID- 19.
  Patient Education and Counseling. http://doi.org/10.1016/j.pec.2021.01.024.
• Haibach, J.P., Hoerster, K.D., Dorflinger, L, McAndrew, L.M., Cassidy, D.G., Goodrich, D.E., Bormann, J.E., Lowery, J., Asch, S.M., Raffa, S.D., Moin, T., Peterson, A.L., Goldstein, M.G., Neal-Walden, T., Talcott, G.W., Hunter, C.L., & Knight, S.J. (2021). Research translation for military and veteran health.
  Research, Practice, Policy. Translational Behavioral Medicine. 11. 631–641. https://doi.org/10.1093/tbm/ibz195
• Kimber, J., Sullivan, N., Anastasides, N., Slotkin, S., & McAndrew, L.M.* (2021). Illness beliefs of Veterans with persistent physical symptoms.
  International Journal of Behavioral Medicine. https://doi.org/10.1016/j.lfs.2021.119219
• Breland, J., Wong, J., & McAndrew, L.M.,* (2020). Are Common Sense Model constructs and self-efficacy simultaneously correlated with self-management behaviors and health outcomes: A systematic review.
  Health Psychology Open. 23;7(1). https://doi.org/10.1177/2055102919898846
• Brunkow, A., Cannon, M., Graff, F.S., Martin, J.L., Hausmann, L.R.M., & McAndrew, L.M.* (2020). Doctor recommendations are related to patient interest and use of behavioral treatment for chronic pain and addiction.
  Journal of Pain. 21. 979-987. https://doi.org/10.1016/j.jpain.2019.12.008
• Fried, D., McAndrew, L.M., Helmer, D.A., & Quigley, K.S. (2020). Physical symptoms with greater functional limitations predict more frequent healthcare utilization in a prospective longitudinal study of soldiers.
  BMC Family Practice. 21. https://doi.org/10.1186/s12875-020-01193-y.
• Sullivan, N., Phillips, L.A., Pigeon, W.R., Quigley, K.S., Graff, F., Litke, D., Helmer, D.A., Rath, J.F., & McAndrew, L.M.* (2019). Coping with medically unexplained physical symptoms: The role of illness beliefs and behaviors.
  International Journal of Behavioral Medicine. 26. 665-672. http://doi: 10.1007/s12529-019-09817-z.
• McAndrew, L.M., Lu, S., Phillips, A. Maestro, K., & Quigley, K.S., (2019). Mutual maintenance of PTSD and physical symptoms for Veterans returning from deployment.
  European Journal of Psychotraumatology. 10, 1608717. https://doi.org/10.1080/20008198.2019.1608717
• McAndrew, L.M., Friedlander, M., Litke, D.A., Phillips, L.A., Kimber, J., & Helmer, D.A. (2019). Medically unexplained physical symptoms: What they are and why counseling psychologists should care about them.
  The Counseling Psychologist. 47(5) 741 –769. http://doi.org/10.1177/0011000019888874
• Phillips LA, McAndrew LA. (2019). Empirical Evaluation of Veterans’ Perceived Non-Concordance with Providers Regarding Medically Unexplained Symptoms.
  The Counseling Psychologist. *
• Anastasides N, Chiusano C, Gonzalez C, Graff F, Litke DR, McDonald E, Presnall-Shvorin J, Sullivan N, Quigley KS, Pigeon WR, Helmer DA, Santos SL, McAndrew LM. (2019). Helpful ways providers can communicate about persistent medically unexplained physical symptoms
  BMC Fam Pract. 20(1):13. doi: 10.1186/s12875-018-0881-8. *
• Friedlander ML., Kangos K., Maestro K., Muetzelfeld H., Wright S., Da Silva N., Kimber, J., Helmer DA, McAndrew, LM. (2019). Medically unexplained physical symptoms: What they are and why counseling psychologists should care about them.
  The Counseling Psychologist.*
• McAndrew LM, Friedlander ML, Alison Phillips L, L Santos S, Helmer DA. Concordance of illness perceptions: The key to improving care of medically unexplained symptoms.
  J Psychosom Res. 2018 Aug;111:140-142. *
• McAndrew LM, Helmer DA, Lu SE, Chandler HK, Slotkin S, Quigley KS. Longitudinal relationship between onset of physical symptoms and functional impairment.
  J Behav Med. 2018 Jun 9. Mental Health.*
• Mohanty, A.F., McAndrew, L.M., Helmer, D., Samore, M.H., & Gundlapalli, A.V. (2018). 
  J Gen Intern Med. DOI: 10.1007/s11606-018-4479-6.
• Phillips, L. A., McAndrew, L., Laman-Maharg, B., & Bloeser, K. (2017). Evaluating challenges for improving medically unexplained symptoms in US military veterans via provider communication.
  Patient Education and Counseling, 100(8), 1580-1587. doi:10.1016/j.pec.2017.03.011
• McAndrew, L. M., Phillips, L. A., Helmer, D. A., Maestro, K., Engel, C. C., Greenberg, L. M., Quigley, K. S. (2017). High healthcare utilization near the onset of medically unexplained symptoms.
  Journal of Psychosomatic Research, 98, 98-105. doi:10.1016/j.jpsychores.2017.05.001
• McAndrew, L. M., Greenberg, L. M., Ciccone, D. S., Helmer, D. A., & Chandler, H. K. (2017). Telephone-Based Versus In-Person Delivery of Cognitive Behavioral Treatment for Veterans with Chronic Multisymptom Illness: A Controlled, Randomized Trial.
  Military Behavioral Health, 6(1), 56-65. doi:10.1080/21635781.2017.1337594
• McAndrew, L. M., Held, R. F., Abbi, B., Quigley, K. S., Helmer, D. A., Pasupuleti, R. V., & Chandler, H. K. (2016). Less Engagement in Pleasurable Activities Is Associated With Poorer Quality of Life for Veterans With Comorbid Postdeployment Conditions.
  Military Psychology, 29(1), 74-81. doi:10.1037/mil0000139
• McAndrew, L. M., Helmer, D. A., Phillips, L. A., Chandler, H. K., Ray, K., & Quigley, K. S. (2016). Iraq and Afghanistan Veterans report symptoms consistent with chronic multisymptom illness one year after deployment.
  Journal of Rehabilitation Research and Development, 53(1), 59-70. doi:10.1682/jrrd.2014.10.0255
• McAndrew, L. M., Mora, P., Quigley, K., Leventhal, E. & Leventhal, H., (2014). Using  the common-sense model of self-regulation to understand symptom reporting.
  International   Journal of Behavioral  Medicine, 1-6, doi:10.1007s/12529-013-9372-4.*
• Li M, Xu C, Yao W, Mahan CM, Kang HK, Sandbrink F, Zhai P, and Karasik PA (2014). Self-reported post-exertional fatigue in Gulf War Veterans: roles of autonomic testing.
  Frontiers in Neuroscience, 7:269.*
• Lange, GL, McAndrew, L, Ashford, JW, Reinhard, M, Peterson, M, Helmer, DA. (2013) War Related Illness and Injury Study Center (WRIISC): A Multidisciplinary Translational Approach to the Care of Veterans With Chronic Multisymptom Illness
  Military Medicine, 178, 7:705.*
• Rumage, C, Falca-Dodson, M, Santos, SL, & Teichman, R. (2011). Medically Unexplained Symptoms in the Veteran Population: Challenges and Opportunities.
  MDAdvisor, 4 (2).*
• Ciccone, D.S., Chandler, H.K., & Natelson, B. (2010). Illness Trajectories in the Chronic Fatigue Syndrome: A Longitudinal Study of Improvers versus Non-Improvers.
  Journal of Nervous and Mental Disease, 198, 486-493.
• Lange, G. (2018). Chronic Fatigue Syndrome, Gulf War Syndrome. In: J.S. Kreutzer, J.DeLuca & B. Caplan (Eds.), Encyclopedia of Clinical Neuropsychology, Springer Verlag, Germany.
• Lange, G. & Natelson, B.H. (2009). Chronic Fatigue Syndrome. In Mayer, E.A. & Bushnell, M.C. (Eds.), Functional Pain Syndromes: Presentation and Pathophysiology (IASP Press).
• Chandler, H.K., Ciccone, D., Macbride, R. J., & Natelson, B. (2007). Medically unexplained illness in short- and long-term disability applicants: Prevalence and cost of salary reimbursement.
  Disability Rehabilitation, 1-7. *
• Natelson, B.H., Intriligator, R., Chandler, H.K., Cherniak, N.S., & Stewart, J.M. (2007). Hypocapnia is a Biological Marker for Orthostatic Intolerance in Some Patients with Chronic Fatigue Syndrome.
  Dynamic Medicine, 6(1):2. *
• Yoshiuchi, K., Cook, D.B., Ohashi, K., Kumano, H., Kuboki, T., Yamamoto, Y. & Natelson, B.H. (2007). A real-time assessment of the effect of exercise in chronic fatigue syndrome.
  Physiology & Behavior, 95, 963-968. *
• Tseng, C.L., Sambamoorthi, U., Helmer, D., Tiwari, A., Rosen, A. K., Rajan, M. et al. (2007). The association between mental health functioning and nontraumatic lower extremity amputations in veterans with diabetes.
  General Hospital Psychiatry, 29, 537-546. *
• Weinstein, S.E. & Quigley, K.S. (2006). Locus of control predicts appraisals and cardiovascular reactivity to a novel active coping task.
  Journal of Personality, 74(3):911-932 *
• Yoshiuchi, K., Farkas, J. & Natelson, B.H. (2006). Patients with chronic fatigue syndrome have reduced absolute cortical blood flow.
  Clinical Physiology and Functional Imaging, 26(2):83-6.*
• Natelson BH, Tseng CL, Ottenweller JE. (2005). Spinal fluid abnormalities in patients with chronic fatigue syndrome.
  Clinical & Diagnostic Laboratory Immunology, 12(1):53-55. *
• Poluri A, Mores J, Cook D, Findley T, Cristian A. (2005). Fatigue in the elderly.
  Phys Med Rehabil Clin N Am., 16(1):91-108. .*
• McCully K, Smith S, Rajaei S, Leigh Jr J, Natelson B. (2004). Muscle metabolism and blood flow restriction in chronic fatigue syndrome.
  Journal of Applied Psychology, 96:871-8.*
• Ohashi K, Bleijenberg G, Natelson BH, Yamamoto Y.(2004). Decreased fractal correlations in diurnal physical activity in chronic fatigue syndrome.
  Methods of Information in Medicine, 43:26-29. *
• Tseng CL, Natelson B. (2004). Few gender differences exist between women and men with chronic fatigue syndrome. Journal of Clinical Psychology in Medical Settings, 11: 55-62, 2004.
• Yoshiuchi K, Quigley KS, Ohashi K, Yamamoto Y, Natelson B. (2004). Use of time-frequency analysis to investigate temporal patterns of cardiac autonomic response during head-up tilt in chronic fatigue syndrome.
  Autonomic Neuroscience, 113: 55-62. *
• Cook DB, Nagelkirk PR, Peckerman A, Poluri A, LaManca JJ, Natelson BH. (2003). Perceived exertion in fatiguing illness part 1: civilians with chronic fatigue syndrome.
  Medicine and Science in Sports and Exercise, 35(4):563-568.*
• McCully KK, Smith S, Rajaei S, Leigh Jr JS, Natelson BH. (2003). Blood flow and muscle metabolism in chronic fatigue syndrome.
  Clinical Science, 104(6):641-647.*
• Peckerman A, LaManca JJ, Qureishi B, Dahl KA, Golfetti R, Yamamoto Y, Natelson BH. (2003). Baroreceptor reflex and integrative stress responses in chronic fatigue syndrome.
  Psychosomatic Medicine, 65:889-895.*
• Peckerman A, LaManca JJ, Dahl K, Qureishi B, Natelson BH. (2003). Abnormal impedance cardiography predicts symptom severity in chronic fatigue syndrome.
  American Journal of Medical Sciences, 326(2):55-60.*
• Yamamoto Y, LaManca J, Natelson BH. (2003). A measure of heart rate variability is sensitive to orthostatic challenge in women with chronic fatigue syndrome.
  Experimental Biology and Medicine, 228(2):167-174.*
• Natelson BH, Haghighi MH, Ponzio NM. (2002). Evidence for the presence of immune dysfunction in chronic fatigue syndrome.
  Clinical and Diagnostic Laboratory Immunology, 9(4):747-752.*
• Natelson BH, Lange G. (2002). A status report on chronic fatigue syndrome.
  Environmental Health Perspectives, 110 Suppl 4:673-677.*
• Ohashi K, Yamamoto Y, Natelson BH. (2002). Activity rhythm degrades after strenuous exercise in chronic fatigue syndrome.
  Physiology and Behavior, 77:39-44.*
• Natelson BH. (2001). Chronic fatigue syndrome.
  JAMA, 285:2557-2559.*
• Ottenweller JE, Sisto SA, McCarty RC, Natelson BH. (2001). Hormonal responses to exercise in chronic fatigue syndrome.
  Neuropsychobiology, 43(1):34-41. *

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